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In the production of agrochemicals, Propionic Acid derivatives exhibit significant biological activity. The O,O-di-propionyl trichlorfon phosphate ester formed by esterification with trichlorfon has an LC50 value of 0.12 mg/L against cotton aphids as a contact insecticide. The 2-chloropropionate herbicide prepared has a half-life of 42 days in soil and an ED90 value of 0.45 kg/ha against weeds. It is important to note that these compounds hydrolyze and become ineffective in environments with pH > 8, requiring the use of buffer agents.